Literature reviews and meta-analyses


Systematic reviews

Application of systematic review methodology to:

  • Drug and diagnostic clinical data
  • Randomised and non-randomised clinical data
  • Observational/epidemiological data
  • HRQoL, utility, HCRU, cost, economic evaluation

Supporting health economic models, HTA submissions, and value message and GVD development


Use of up-to-date methodology in a complex and rapidly evolving field

All types of meta-analysis, including:

  • Pairwise meta-analyses
  • Network meta-analyses (NMA)
  • Single arm comparisons
    • Matched-adjusted indirect comparisons (MAIC)
    • Simulated treatment comparisons (STC)
    • Meta-regressions

Other reviews

Targeted and pragmatic reviews to support market access deliverables

  • Health economic models
  • Value propositions
  • Briefing books
  • Early evidence dossiers
  • Global value dossiers
  • HTA submissions (where systematic review methodology is not required)